March 2, 2026 4:47 PM

Indian scientists challenge 50-year-old model of bacterial gene regulation

In a breakthrough that could reshape fundamental understanding of bacterial biology, Indian scientists have helped overturn a long-standing textbook model explaining how bacteria switch their genes on and off. A new study led by researchers from the Bose Institute, an autonomous institute under the Department of Science and Technology (DST), in collaboration with Rutgers University, challenges the widely accepted “sigma (σ) cycle” model of bacterial gene regulation that has dominated biolo...