October 19, 2024 11:48 AM

mRNA vaccine shows promise against C. difficile in animal study

Researchers are developing what they hope will be the first successful vaccine against the highly contagious and difficult-to-treat Clostridioides difficile bacteria, using the technology behind the revolutionary mRNA vaccines that tackled the coronavirus that caused COVID-19. In mice and in nonhuman primates, the experimental mRNA vaccine protected against first-time infections with C. difficile and also against relapsing infections, researchers reported in Science. Earlier attempts at produc...