Alzheimer’s disease

December 26, 2025 10:30 AM

Animal studies show Alzheimer’s disease can be reversed

In a significant breakthrough, US researchers have found in animal studies that Alzheimer’s disease can be reversed, challenging a long-held belief that the neurodegenerative disorder is irreversible. The study, published in the journal Cell Reports Medicine, was based on diverse preclinical mouse models and human Alzheimer’s brain samples. It showed that maintaining proper NAD+ balance in the brain can not only prevent but also reverse the disease. NAD+ is a key cellular energy molecule a...

December 16, 2025 12:22 PM

Indian researchers develop nanoparticle-based multi-target therapy for Alzheimer’s

A new nanoparticle-based therapy developed by Indian researchers could pave the way for a more comprehensive and effective treatment for Alzheimer’s disease by targeting multiple pathological mechanisms simultaneously, according to a study released on Tuesday. Researchers at the Institute of Nano Science and Technology (INST), Mohali — an autonomous institute under the Department of Science and Technology (DST) — have developed a multifunctional nanoplatform that integrates an antioxidant...

October 12, 2025 4:14 PM

National strategy on ageing, mental health key to fight Alzheimer’s in India, say experts

India needs a national strategy on ageing and mental health to address the rising cases of Alzheimer’s disease in the country, according to health experts. In an editorial published in the Indian Journal of Public Health, experts from the Ministry of Health and Family Welfare, along with M.M. Medical College and Hospital, Himachal Pradesh, highlighted the need to implement a comprehensive National Dementia Plan aligned with the World Health Organization’s global framework. “India needs t...

September 21, 2025 2:00 PM

Link between vascular disease, dementia risk overlooked: study

Vascular dementia, a form of cognitive decline caused by disease in the brain’s small blood vessels, remains under-researched compared to Alzheimer’s disease, despite its widespread impact, according to a new study. Researchers at the University of New Mexico have developed a model to better characterise and categorise different forms of vascular dementia, aiming to deepen understanding and pave the way for effective treatments. While conditions such as hypertension, atherosclerosis, and d...

August 16, 2025 5:08 PM

Study explains why loss of smell is linked to Alzheimer’s disease

The brain’s immune cells may explain why a fading sense of smell is an early indicator of Alzheimer’s disease, even before cognitive impairments appear, according to a new study. Researchers at DZNE and Ludwig-Maximilians-Universität München (LMU) in Germany found that the brain's immune response seems to fatally attack neuronal fibres critical for the perception of odours. These olfactory dysfunctions arise because immune cells in the brain, called microglia, remove connections between ...

July 19, 2025 12:03 PM

Scientists find over 200 hidden proteins that may drive Alzheimer’s: Study

A groundbreaking study has uncovered more than 200 previously undetected misfolded proteins in the brains of aging rats with cognitive decline, offering new insights into the mechanisms of Alzheimer’s and other forms of dementia. Unlike the well-known amyloid and tau proteins that clump into visible plaques, these newly identified proteins do not form detectable aggregates, making them harder to identify—but potentially just as damaging to brain function. Scientists belie...